Yes,
@Ploshkin @sleepingwolf I have a drawer full of hand knitted socks and have cuff down, cuff up and all the the different heels and toes but definitely for me cuff down with a flap and gusset heel and a pointy round toe (not sure of the "official" name) works best for me.
I do sometimes try on but with cuff down I find that holding the folded heel against the centre back of my heel works just as well. I knit until the work is level with my little toe nail and then start the toe decreases.
I have developed my own sock pattern - which I can now do without referring to it! The instructions are at
http://paternoster.orpheusweb.co.uk/knitting/ScrapBusterSocks.pdfDesigned to use up scraps but it works just as well with a single ball of yarn, without all the ends to darn in.