I have a Brother Innovis 2200, combined machine, which I love using. It is easy to use has put up with anything I've thrown at it.
For my 60th I treated myself to a new machine and got a Janome 4950 QCP, which I use but don't enjoy using like the Brother.
The needle threader on the Brother just works perfectly, the needle threader on the Janome, hardly ever works although everything else does.
As
@Ohsewsimple says it really is personal preference and I wish I had not got the Janome without trying it out first.