Regard the sewing as preparation for tidying the room. Getting the ergonomics and the work flow area just right, and of course, the right feng shui.
Then you may have to do a risk assessment on the area before you make any decisions as to placement of machines. And
then you have to find out who to submit the reports to.
Realistically, it could take months before you can even start to consider starting to arrange things.
I'd sit down & have a glass of red medicine now if I were you. Just to help the decision making process of course.
And the quilts are gorgeous.