As long as there is not a one way pattern or any nap, and it is on the same grain, yes. I will lay the fabric out on the table and walk around it from all angles to look at it and if there is a small swatch I can cut off, I'll take it outside and look in the sun. Most of the time, I use a linen prover/tester to look at the threads to ensure the warp and weft are the same.
All sounds like a lot of work, takes just a few minutes at most. Glance at the fabric from all angles, use the tester, walk outside flip the fabric about.
I can only recall one fabric I've used that had no nap or one way design that it didn't work on. It looked okay with the naked eye, but something was "off" and when I looked at it with the tester, the dye had every few threads shaded different one way from the other. And most people would never notice the difference.
Also: modern factories do not worry about grain. If it fits, it doesn't matter where the grain is. So you are also pretty safe is flipping considering what they do.
Edit: you can also piece together the parts you need. Neck with seam instead of on fold. I have a McCalls top I like from Palmer and Pletsch, but the shirt calls for 3 yards and I have never been able to get it on with their layout under 4 unless I add a back seam.